How Substances Affect Both Sleep and Chronic Pain: The Science Behind Caffeine, Alcohol, Nicotine, and Soda

by 
Override Health

For many of us, substances like caffeine, alcohol, nicotine, and soda are everyday staples. Need to wake up? Coffee. Need to unwind? A glass of wine. Feeling stressed? A cigarette or a soda might feel like a good solution. But while these substances can deliver what feels like relief or energy in the moment, they often come with hidden costs—especially when it comes to sleep and chronic pain.

If you’re someone dealing with chronic pain, you already know that sleep and pain are deeply connected. Poor sleep makes pain worse, and more pain makes it harder to sleep. It’s a vicious cycle. Add in the effects of caffeine, alcohol, nicotine, or soda, and things can spiral quickly. Here’s how these substances sneak into this cycle and make it even harder to break.

Caffeine: The Double-Edged Sword

Caffeine, a staple for millions, is a powerful stimulant found in coffee, tea, energy drinks, and many sodas. While it can help improve focus and temporarily reduce feelings of fatigue, it has a significant downside when it comes to sleep.

Impact on Sleep

Caffeine blocks adenosine, a neurotransmitter that promotes sleepiness, which can delay the onset of sleep and reduce overall sleep quality. Its half-life of around 5–6 hours means it can linger in your system, especially if consumed later in the day. For individuals with chronic pain, disrupted sleep can exacerbate pain perception, making it harder to manage symptoms.

Impact on Chronic Pain

Studies suggest that while caffeine can sometimes provide short-term pain relief—such as in medications for headaches like Excedrin—habitual consumption may worsen chronic pain conditions. Poor sleep caused by caffeine intake heightens the body’s sensitivity to pain and reduces its ability to recover, creating a feedback loop of discomfort.

Alcohol: A False Friend of Sleep

Alcohol is often used as a social lubricant or a way to unwind after a stressful day. While it may seem to induce relaxation, its effects on sleep and chronic pain tell a different story.

Impact on Sleep

Alcohol may help you fall asleep faster, but it disrupts the architecture of sleep by reducing REM (rapid eye movement) sleep, a critical stage for mental and physical restoration. It also fragments sleep, causing frequent awakenings throughout the night. For chronic pain sufferers, the lack of restorative and good quality sleep can intensify pain signals and reduce pain tolerance.

Impact on Chronic Pain

Chronic alcohol consumption can worsen inflammation, a key contributor to many chronic pain conditions such as arthritis and fibromyalgia. Additionally, alcohol’s numbing effects might mask pain temporarily, but over time, it can lead to dependency and exacerbate underlying issues.

Nicotine: A Sleep and Pain Disruptor

Nicotine, the active ingredient in cigarettes, vaping products, and tobacco, is another commonly used substance with profound effects on sleep and chronic pain.

Impact on Sleep

Nicotine is a stimulant that increases heart rate and alertness, making it harder to fall and stay asleep. Smokers are more likely to suffer from sleep disorders such as insomnia and sleep apnea. The fragmented and poor-quality sleep caused by nicotine can lead to increased pain perception and decreased pain tolerance.

Impact on Chronic Pain

Nicotine affects the nervous system by altering the way pain signals are processed. While some may experience short-term relief due to its effect on dopamine release, long-term use worsens chronic pain by reducing blood flow and exacerbating conditions like back pain and nerve damage.

Soda: More Than Just Empty Calories

Soda, whether caffeinated or not, diet or regular, poses unique risks due to its high sugar content and, often, caffeine. While many people enjoy it as a quick pick-me-up, soda’s impact on sleep and pain cannot be ignored.

Impact on Sleep

Caffeinated sodas share the same sleep-disrupting properties as other sources of caffeine. However, even non-caffeinated sodas can interfere with sleep due to their high sugar (or sugar alternatives) content. Spikes and crashes in blood sugar levels can lead to nighttime awakenings, further reducing sleep quality.

Impact on Chronic Pain

Excess sugar in soda promotes systemic inflammation, a key driver of chronic pain conditions. Frequent soda consumption has been linked to worsening symptoms in conditions like rheumatoid arthritis and migraines. The disrupted sleep caused by soda’s effects further compounds its impact on pain.

Breaking the Cycle

The interplay between these substances, sleep, and chronic pain highlights the importance of lifestyle choices in managing overall health. While eliminating these substances entirely may not be realistic for everyone, moderation and timing can make a significant difference.

Start Here:

  • Caffeine: Cut it off by 2 p.m. (or earlier) and swap that evening coffee for herbal tea.
  • Alcohol: Limit it to occasional use and try to avoid it within three hours of bedtime.
  • Nicotine: Reducing or quitting is a game changer—not just for sleep and pain, but for your overall health.
  • Soda: Replace it with flavored water or seltzer. You will still get the carbonated affect and can view it as a treat, but without the negative health repercussions.

Your body (and your sleep) will thank you.

The Bottom Line

What you put into your body matters, especially if you’re dealing with chronic pain. Substances like caffeine, alcohol, nicotine, and soda might feel like quick fixes, but they can disrupt the very systems your body relies on to heal and function. By making mindful choices—like adjusting when and how you consume these substances—you can start to untangle the cycle of poor sleep and chronic pain.

Small steps lead to big changes, and every positive choice gets you closer to feeling a little bit better.

Posted on 
January 3, 2025

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